网页1984/07/01 · The diffusion test in combination with the BP test provides decisive information for the acceptance of a filter element in sterile filtration. The single point diffusion test as usually performed is capable of detecting a flaw of 5 to 10 μm in size for large area membrane filters. Because of the amount and variability of gas flow through large area
网页2017/09/15 · Integrity test measurements depend on the surface area of the filter, the polymer of the membrane, the wetting fluid, the pore size of the membrane, and the gas used to perform the test. Wetting fluids may have different surface tensions, which can depress or elevate the bubble point pressure. The use of different test gases may elevate
网页Figure 1: Typical layout for an Integrity Test System PROCEDURE NOTES • If the filter application is bacteria removal, then the filter and system should be tested using sterile water and air (filtered to 0.22 microns or smaller
网页This document describes how to use the Integrity Test Kit for small volume devices to integrity test non-vented and vented filter units with membrane surface areas of less than 15 cm 2 (2.3 in 2). Larger devices can be integrity tested
网页Cytiva has developed a capillary flow porometry test to confidently and efficiently characterize the pore structure of hollow fiber filtration membranes before manufacturing the cartridges. Capillary flow porometry is particularly effective in measuring the pore size distribution for the full range of Cytiva microfiltration products down to and
网页2021/06/08 · Read on to learn about each of the three main filter integrity tests. 1. Diffusion Test (also known as “ forward flow ”) A diffusion test applies a constant pressure of air on the upstream side of a filter saturated with liquid and measures the volume of air over time that diffuses through the filter. The liquid is usually water, and this
网页2022/04/06 · Integrity Test. Turn off the water pump, close valves 2 and 4, open valve 3, connect the machine air pipe to the instrument connection port, and then open valve 1 to do the testing. It is recommended that customers test the diffusion flow data first, and then test the bubble point data. 4. Matters Need Attention.
网页vent the filter. 10. Depressurize pressure tank and open V1 to drain the wetting fluid from the upstream side into the tank. 11. Close V1 and disconnect pressure vessel from system. 12. Connect an integrity tester to V2, ensure the
